Want to be More Kysse-able

iStock 591836306 Last summer, we introduced a new filler for the lips to our Mt. Pleasant clients Restylane Kysse. Kysse is the newest filler in the ever-expanding Restylane line, and AesthetiSpa was thrilled to offer the first practice in the coastal Carolina area to offer it. 

In April of 2019, although no one really noticed thanks to the pandemic that was just beginning to sweep the nation, the FDA approved Kysse. Kysse is intended specifically to add volume and smooth lines on the lips. 

At AesthetiSpa, we’ve long used Restylane Silk to add volume and definition to the lips. But Kysse has some aspects that could make it the preferred option for lip volume for some time. And as we’re now in the scary month of October, this could be a good time to come in to add some shape to your lips for the upcoming holiday season. 

What is Restylane Kysse? 

Restylane Kysse is a clear injectable gel composed of hyaluronic acid. Hyaluronic acid is a naturally occurring sugar in the human body that is responsible for hydrating and plumping the skin. It does this by binding with nearby water molecules. 

Restylane Kysse is specifically meant for use on the lips. Once injected, Kysse adds fullness to the lips and it helps smooth wrinkles above the upper lip (perioral lines). 

It is available for patients over the age of 21. 

What’s the difference with Kysse? 

Kysse is the first dermal filler to be equipped with Optimal Balance Technology, also known as XpresHAn Technology. This technology enables Kysse to integrate into the tissues in the injected areas to achieve a more natural look. 

Restylane Kysse is meant as a complement to Restylane Silk, which is also formulated for the lips. Silk delivers more volume, while still looking natural. Kysse is intended to add soft, subtle volume to the lips, while also smoothing wrinkles around the mouth. 


To gain FDA approval, Galderma (the maker of Restylane) had to show satisfaction rates with patients in their testing of Kysse. Those phase 3 trial patients reported these results: 

  •     Participants noted improvement in lip fullness using a lower amount of filler when using Kysse versus other fillers.
  •     78% of participants reported satisfaction with their lip volume and lip appearance 1 year after their injections.

What are the side effects with Kysse? 

The side effects with this new Restylane filler are the same as those with all hyaluronic acid fillers: possible bruising and redness at injections sites, possible lumps or nodules, and sensitivity at the injection sites. If lumps do form, they are easily removed with an injection of an enzyme that neutralizes the hyaluronic acid and erases the lumps. 

Interested in adding shape to your lips? Call AesthetiSpa at 843-849-9925 to schedule a consultation and appointment for Kysse.

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